Chacaleria is a crime film about Antonia, a self-made entrepreneur who, after losing her livelihood to the COVID-19 pandemic, wants to secure her financial future by selling and distributing alcohol illegally using a drone during Panama's nationally mandated dry law. This becomes increasingly difficult when Ronny, a by the book cop, who is forced to be corrupt, catches Antonia in the act and blackmails her into robbing a bank.