UFC 122: Marquardt vs. Okami was a mixed martial arts event held by the Ultimate Fighting Championship on November 13, 2010 at König Pilsener Arena in Oberhausen, Germany. Vitor Belfort was set to face Yushin Okami in the main event, with the winner receiving a middleweight title shot. However, on September 21, 2010, Belfort withdrew from the fight to face Anderson Silva. Nate Marquardt ended up fighting Yushin Okami in the main event, which would still determine the next #1 contender.